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Hi Eric,

Good analogy. It could be tweaked a little bit. Someone may suppose that there are new fruits in the rainforest. They go and take some samples of debris on the forest floor. They put them through sequencing and find some RNA that is similar to a grapefruit. The computer adds in the most probable sequences and they get a covfruit. No one has yet seen a covfruit, but they know it must exist because they have the genome.

They develop a PCR test using markers in covfruit. They could then go to the supermarkets and sweep up the debris in the produce aisle. When they do a PCR test, they all test positive for covfruit, but still, no one has seen one yet. They could go out in the jungle and look for one, except they don't know what it looks like, what color it is or how big or small it is outside their best guess.

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